Brain

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A Phase 3, Randomized, Open-Label Study to Evaluate the Efficacy and Safety of Eflornithine with Lomustine Compared to Lomustine Alone in Patients with Anaplastic Astrocytoma That Progress/Recur After Irradiation and Adjuvant Temozolomide Chemotherapy (STELLAR Study)

The purpose of this study is to compare the efficacy and safety of eflornithine in combination with lomustine, compared to lomustine taken alone,...

Santosh Kesari, M.D.
  • John Wayne Cancer Institute (JWCI)
  • Providence St. Johns Health Center (PSJHC)

AtRial Cardiopathy and Antithrombotic Drugs In Prevention After Cryptogenic Stroke

Inclusion Criteria:-Age ≥ 45 years.-Clinical diagnosis of ischemic stroke + brain imaging to rule out hemorrhagic stroke.-Modified Rankin Scale...

Sheila Smith, M.D.
  • Swedish Medical Center

A Longitudinal Assessment of Tumor Evolution in Patients with Brain Cancer

This is a prospective, multi-center, open-label, randomized, multi-arm exploratory study to assess the safety and tolerability of nivolumab and...

Santosh Kesari, M.D.
  • John Wayne Cancer Institute (JWCI)
  • Providence St. Johns Health Center (PSJHC)

A Phase 0/1 Study of Combination Drug Therapy For Glioblastoma Based on Personalized Cancer Stem Cell (CSC) High-Throughput Drug Screening (HTS)

A study to determine the safety of CSC/ HTS-based combination drug therapy in subjects who have GBM that has recurred or progressed following prior...

Charles Cobbs, M.D.
  • Swedish Medical Center

Phase II trial of autologous dendritic cells loaded with autologous tumor associated antigens (AV-GBM-1) as an adjunctive therapy following primary surgery plus concurrent chemoradiation in patients with newly diagnosed glioblastoma.

PHASE II TRIAL OF AV-GBM-1 (AUTOLOGOUS DENDRITIC CELLS LOADED WITH AUTOLOGOUS TUMOR ASSOCIATED ANTIGENS) AS ADJUNCTIVE THERAPY FOLLOWING PRIMARY...

Michael Duma, M.D.
  • Hoag Research
  • xSJH Southern California

Genomically-Guided Treatment Trial in Brain Metastases.

This phase II trial studies how well genetic testing works in guiding treatment for patients with solid tumors that have spread to the brain....

Alison Conlin, M.D.

The Pacific Cancer Research Consortium clinical trials are offered at multiple locations throughout Oregon, Washington, Alaska, California, and Idaho. To find a location near you, please contact the Patient Engagement Center at 844-552-2734.

An Expanded Access Protocol for the Treatment of Glioblastoma Multiforme in Patients with Already Manufactured DCVax-L, Autologous Dendritic Cells Pulsed with Tumor Lysate Antigen Who Have Screen-Failed Protocol 020221

The study is an open-label expanded access study for patients for whom vaccine was manufactured during the Northwest Biotherapeutics' 020221...

Charles Cobbs, M.D.
  • Swedish Medical Center

A Phase I Dose Escalation and CNS Pharmacokinetic Study of the ErbB Family Inhibitor Afatinib in Patients with Recurrent or Progressive Brain Cancer

The purpose of this study is to try to determine the maximum safe dose of afatinib that can be administered to people with brain cancer. Other...

Santosh Kesari, M.D.
  • John Wayne Cancer Institute (JWCI)
  • Providence St. Johns Health Center (PSJHC)

Neurological Outcomes in Health and Disease

This is a non-therapeutic, non-interventional, prospective study. A comprehensive analysis ofsystematically collected functional and anatomical...

Santosh Kesari, M.D.
  • John Wayne Cancer Institute (JWCI)
  • Providence St. Johns Health Center (PSJHC)

The Role of Cidofovir and Structural Analogs as Adjuvant Therapy for Glioblastoma

This project is designed to improve outcomes for brain tumor patients by establishing that Cidofovir and/or its analogs, when combined with...

Charles Cobbs, M.D.
  • Swedish Medical Center
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Viewing Page 1 of 2 | Showing Results 1 - 10 of 18