ONC_AHEP1531

Pediatric Hepatic Malignancy International Therapeutic Trial (PHITT)

This partially randomized phase II/III trial studies how well cisplatin and combination chemotherapy works in treating children and young adults with hepatoblastoma or liver cancer after surgery. Drugs used in chemotherapy, such as cisplatin, doxorubicin, fluorouracil, vincristine sulfate, carboplatin, etoposide, irinotecan, sorafenib, gemcitabine and oxaliplatin, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving combination chemotherapy after surgery may kill more tumor cells.
Phase II/III
NCT03533582
Cancer
Pediatric
Brenda Wittman, M.D.
COG (Childrens Oncology Group)
Brittany Ledall
  • Alaska Pediatric Oncology
  • Alaska Research
  • Providence Alaska Medical Center