The CREST-2 Registry

The objective of C2R is to promote the rapid initiation and completion of enrollment in the CREST-2 randomized clinical trial ( ID NCT02089217). Patients with severe symptomatic and asymptomatic carotid artery occlusive disease will be treated with carotid artery stenting (CAS) performed by experienced and skilled interventionists.

Key Eligibilities:
-Patients aged 18 - 80 years old with symptomatic or asymptomatic carotid artery disease.

Exclusion Criteria:
-Patients with any one of the following conditions are ineligible for enrollment in C2R: NYHA Class IV congestive heart failure, COPD on chronic continuous oxygen therapy, severe (Class Childs D) liver failure, end-stage renal failure requiring dialysis, cancer with metastatic spread and/or undergoing active chemotherapeutic treatment, any dementia considered greater than 'mild.'

**Other protocol-defined inclusion/exclusion criteria may apply. Please click on the NCT Number (below) to learn more about the study at**
Ethan Korngold MD
University of Maryland-Baltimore
Emily Johnson
  • Providence Portland Medical Center
  • Providence St. Vincent Medical Center